We knew the importance of the security and want to ensure it by turning on the Safe Mode. We then have to tell you that whether the safe mode on or off, it will never concern with the security of server. At the present day, PHP have canceled their safe mode as they mentioned that, it is architecturally incorrect to try to solve the security problem. 

You can see more informations here: PHP Manual

You should set the safe mode off, you will then publish your website in effective.